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What Atomoxetine is and how it works

Atomoxetine is a selective norepinephrine reuptake inhibitor used to treat ADHD. It works by blocking the brain's reabsorption of norepinephrine, increasing its levels in the prefrontal cortex to help with attention and impulse control.

It is a non-stimulant medicine. You take it every day, and the benefit comes gradually as norepinephrine builds up in the brain regions that guide focus and self-control. You may notice improvements over weeks, not hours or days.

Common medical uses

Atomoxetine is approved to treat ADHD in children around age six and older, teens, and adults. It can help reduce hyperactivity and impulsive actions while improving attention and organization.

Your doctor will explain how Atomoxetine fits with your symptoms. In some cases, clinicians may use it for related concerns or when stimulants are not suitable, but its main use remains ADHD management with a steady daily dose.

How it is typically taken

Take Atomoxetine exactly as prescribed. The capsule is swallowed whole with a drink. You can take it with or without food, but taking it at the same time each day helps you remember it. Some people start in the morning to avoid sleep problems.

Most people begin at a low dose and slowly raise it over several weeks. Do not chew or crush the capsule, as this changes how the medicine is released in your body. If you miss a dose, take it as soon as you remember unless it is nearly time for your next dose.

Important safety information

Tell your doctor about any medical conditions you have, and about all medicines you take, including supplements. Do not take monoamine oxidase inhibitors (MAO inhibitors) with atomoxetine or within two weeks of stopping them. Your doctor can guide you safely with other medicines you may use.

Atomoxetine can raise blood pressure and heart rate in some people. Have your blood pressure and heart rate checked as advised, and report chest pain, fainting, or severe headaches. In rare cases, liver injury can occur; seek medical help if you notice yellowing of the skin or eyes, dark urine, or persistent abdominal pain.

Common side effects

Common side effects include stomach upset, nausea, decreased appetite, and dry mouth. Some people also feel dizziness, tiredness, or trouble sleeping. You may notice these early on as your body adjusts to the medicine.

Most side effects fade with time. If side effects are bothersome, persist, or suddenly feel severe, talk to your doctor. Seek medical help right away for any signs of a serious reaction or if you have thoughts of harming yourself or others. Do not stop atomoxetine suddenly without medical advice.

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14–21 days. Free from €175.76 .

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All orders are packed in neutral, unbranded boxes with no product name on the outside.

Siobhan O'Connor
Medically reviewed by
Siobhan O'Connor
General Practitioner (MD)